POLYPHOSPHATE-HYDROLYSIS - A PROTECTIVE MECHANISM AGAINST ALKALINE STRESS

被引：68

作者：

PICK, U

BENTAL, M

CHITLARU, E

WEISS, M

机构：

[1] UNIV PENN,DEPT PHYSIOL,PHILADELPHIA,PA 19104

[2] JOHNS HOPKINS UNIV,DEPT BIOL,BALTIMORE,MD 21218

来源：

FEBS LETTERS | 1990年 / 274卷 / 1-2期

关键词：

Dunaliella; pH regulation; Polyphosphate;

D O I：

10.1016/0014-5793(90)81318-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Different microorganisms, including yeast and algae, accumulate large amounts of polyphosphates. However, the physiological role of polyphosphates is largely unknown. In vivo 31P NMR studies, carried out in the unicellular alga, Dunaliella salina, demonstrate that cytoplasmic alkalization induces massive hydrolysis of polyphosphates, which is correlated kinetically with the recovery of cytoplasmic pH. Analysis of acid extracts of the cells indicates that long-chain polyphosphates are hydrolysed mainly to tripolyphosphate. It is suggested that the hydrolysis of polyphosphates provides a pH-stat mechanism to counterbalance alkaline stress. © 1990.

引用

页码：15 / 18

页数：4

共 14 条

[1]

BASSET J, 1978, VOGELS TXB QUANTITAT, P730

[2] METABOLIC STUDIES WITH NMR-SPECTROSCOPY OF THE ALGA DUNALIELLA-SALINA TRAPPED WITHIN AGAROSE BEADS [J].