BOWENS DISEASE (SQUAMOUS-CELL CARCINOMA INSITU) AS A SKIN MARKER FOR INTERNAL MALIGNANCY - A CASE-CONTROL STUDY

被引：14

作者：

CHUANG, TY ^{[1
]}

TSE, J ^{[1
]}

REIZNER, GT ^{[1
]}

机构：

[1] UNIV WISCONSIN HOSP & CLIN,DERMATOL SECT,MADISON,WI 53792

来源：

AMERICAN JOURNAL OF PREVENTIVE MEDICINE | 1990年 / 6卷 / 04期

关键词：

D O I：

10.1016/S0749-3797(18)31010-9

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Bowen's disease has been viewed as a skin marker for internal malignancy by dermatologists for decades. If substantiated, it certainly would help in early detection of an occult malignancy. We conducted a matched case-control study to evaluate the significance of this link. Ninety patients with Bowen's disease diagnosed between 1972 and 1986 were selected for study. These patients were matched by age, sex, race, and date of biopsy for diagnosis (or treatment) to 90 other patients chosen as controls. Six patients in the Bowen's disease group and three patients in the control group had internal malignancy during the period after the date of biopsy or treatment (P > 0.4). The present study cannot substantiate the claim that Bowen's disease is a skin marker for internal malignancy.

引用

页码：238 / 243

页数：6