FUNDAMENTAL AND CLINICAL ASPECTS OF ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES (ANCA)

被引：20

作者：

HAGEN, EC

BALLIEUX, BEPB

DAHA, MR

VANES, LA

VANDERWOUDE, FJ

机构：

[1] University Hospital, Department of Nephrology, Leiden

来源：

AUTOIMMUNITY | 1992年 / 11卷 / 03期

关键词：

ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES; VASCULITIS; GLOMERULONEPHRITIS;

D O I：

10.3109/08916939209035155

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Anti-neutrophil cytoplasmic antibodies (ANCA) are associated with different forms of both primary and secondary vasculitis and glomerulonephritis. These antibodies are directed against different enzymes located in granulocyte granules. In this review ANCA-related antigens and solid phase assays for ANCA detection will be discussed. Furthermore, we will address the clinical relevance of ANCA and will deliberate on their possible pathogenic implications. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：199 / 207

页数：9

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