ADDITION OF DIMETHYLOXOSULFONIUM METHYLIDE TO ENANTIOMERICALLY PURE SULFINIMINES - ASYMMETRIC-SYNTHESIS OF 2-SUBSTITUTED AZIRIDINES

被引：71

作者：

DAVIS, FA

ZHOU, P

LIANG, CH

REDDY, RE

机构：

[1] Department of Chemistry, Drexel University, Philadelphia

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 07期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/0957-4166(95)00185-R

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Diastereoselective addition of dimethyloxosulfonium methylide to chiral nonracemic pure sulfinimines 1 affords N-sulfinyl aziridines 3 in 58-70% de which are readily separated. The N-sulfinyl auxiliary in 3 was removed, without ring-opening, by treatment with MeLi.

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页码：1511 / 1514

页数：4

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