POSITRON EMISSION TOMOGRAPHY IN SCHIZOPHRENIC-PATIENTS WITH AND WITHOUT NEUROLEPTIC MEDICATION

被引：167

作者：

DELISI, LE ^{[1
]}

HOLCOMB, HH ^{[1
]}

COHEN, RM ^{[1
]}

PICKAR, D ^{[1
]}

CARPENTER, W ^{[1
]}

MORIHISA, JM ^{[1
]}

KING, AC ^{[1
]}

KESSLER, R ^{[1
]}

BUCHSBAUM, MS ^{[1
]}

机构：

[1] NIMH, CLIN BRAIN IMAGING SECT, BETHESDA, MD 20205 USA

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1985年 / 5卷 / 02期

关键词：

D O I：

10.1038/jcbfm.1985.26

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Positron emission tomography using [18F]2-fluoro-2-deoxy-D-glucose was performed in 9 chronic schizophrenic patients both when medication-free and when medicated with neuroleptics. Total braincortex temporal cortex and basal ganglia glucose use was significantly increased with medication; however, there was no change in anterior posterior metabolic gradients.

引用

页码：201 / 206

页数：6

共 23 条

[1] BRODIE JD, 1984, ANN NEUROL, V15, pS166
[2] BUCHSBAUM MS, 1982, ARCH GEN PSYCHIAT, V39, P251
[3] BUCHSBAUM MS, 1984, ARCH GEN PSYCHIAT, V41, P1159
[4] BUCHSBAUM MS, 1983, LATERALITY PSYCHOPAT, P559
[5] ANTIPSYCHOTIC-DRUGS, NEUROTRANSMITTERS, AND SCHIZOPHRENIA
CARLSSON, A
[J]. AMERICAN JOURNAL OF PSYCHIATRY, 1978, 135 (02) : 164 - 173
[6] DELISI LE, 1985, AM J PSYCHIAT, V142, P78
[7] DELISI LE, 1985, BIOL PSYCHIATRY
[8] Farkas T., 1980, Cerebral Metabolism and Neural Function, P403
[9] HOFFMAN EJ, 1984, ANN NEUROL, V15, pS25
[10] ABNORMALITIES OF CEREBRAL BLOOD-FLOW DISTRIBUTION IN PATIENTS WITH CHRONIC SCHIZOPHRENIA
INGVAR, DH
FRANZEN, G
[J]. ACTA PSYCHIATRICA SCANDINAVICA, 1974, 50 (04) : 425 - 462

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