SELECTIVE DEFICITS IN COGNITION AND MEMORY IN HIGH-FUNCTIONING PARKINSONIAN-PATIENTS

被引：60

作者：

MOHR, E

JUNCOS, J

COX, C

LITVAN, I

FEDIO, P

CHASE, TN

机构：

[1] NINCDS,MED NEUROL BRANCH,BETHESDA,MD 20205

[2] NINCDS,EXPTL THERAPEUT BRANCH,BETHESDA,MD 20205

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1990年 / 53卷 / 07期

关键词：

D O I：

10.1136/jnnp.53.7.603

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To evaluate the profile and extent of cognitive deficits in Parkinson's disease, afflicted pateints of exceptional professional distinction, who continue to function successfully in leadership positions, were compared neuropsychologically to neurologically normal individuals, matched for sex, age, education and professional standing. While patients showed relative preservation of verbal skills and higher executive function, they exhibited a significant reduction in episodic memory and visuospatial function. The observation of circumscribed impairment in this select group of Parkinsonian patients further implicates cognitive and memory deficits as consistent features of Parkinson's disease.

引用

页码：603 / 606

页数：4

共 35 条

[1] PARALLEL ORGANIZATION OF FUNCTIONALLY SEGREGATED CIRCUITS LINKING BASAL GANGLIA AND CORTEX [J].