TESTICULAR FUNCTION AFTER CHEMOTHERAPY FOR OSTEOSARCOMA

被引：18

作者：

SIIMES, MA ^{[1
]}

ELOMAA, I ^{[1
]}

KOSKIMIES, A ^{[1
]}

机构：

[1] HELSINKI UNIV HOSP, DEPT RADIOTHERAPY & ONCOL, SF-00290 HELSINKI, FINLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1990年 / 26卷 / 09期

关键词：

D O I：

10.1016/0277-5379(90)90623-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Testicular volume, sperm count and four hormones were measured in 18 patients 1-13 years after chemotherapy for osteosarcoma. The testicles were small in 13 patients. 17 patients gave semen samples:10 were azoospermic and 2 were oligozoospermic. Testicular volume and sperm count were possibly associated with the type of chemotherapy. Of the 7 patients who had received cisplatin-containing chemotherapy, 6 had small testes and azoospermia; 1 was oligozoospermic with normal-sized testes. In 3 of the 11 patients whose chemotherapy had not included cisplatin, testicular size and sperm count were normal.

引用

页码：973 / 975

页数：3

共 16 条

[1] HORMONAL CHANGES IN PUBERTY .1. CORRELATION OF SERUM LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE WITH STAGES OF PUBERTY, TESTICULAR SIZE, AND BONE AGE IN NORMAL BOYS [J].

BURR, IM ;

SIZONENKO, PC ;

KAPLAN, SL ;

GRUMBACH, MM .

PEDIATRIC RESEARCH, 1970, 4 (01) :25-+

[2]

CHAPMAN RM, 1979, LANCET, V1, P285

[3]

Dein R A, 1984, Obstet Gynecol Surv, V39, P474, DOI 10.1097/00006254-198408000-00002

[4]

DEVITA VT, 1981, CANCER, V47, P1, DOI 10.1002/1097-0142(19810101)47:1<1::AID-CNCR2820470102>3.0.CO

[5]

2-2

[6] FERTILITY AFTER CHEMOTHERAPY FOR TESTICULAR CANCER [J].

DRASGA, RE ;

EINHORN, LH ;

WILLIAMS, SD ;

PATEL, DN ;

STEVENS, EE .

JOURNAL OF CLINICAL ONCOLOGY, 1983, 1 (03) :179-183

[7] GONADAL FUNCTION, TESTICULAR HISTOLOGY, AND MEIOSIS FOLLOWING CYCLOPHOSPHAMIDE THERAPY IN PATIENTS WITH NEPHROTIC SYNDROME [J].

ETTELDORF, JN ;

WEST, CD ;

PITCOCK, JA ;

WILLIAMS, DL .

JOURNAL OF PEDIATRICS, 1976, 88 (02) :206-212

[8] TESTICULAR FUNCTION FOLLOWING COMBINATION CHEMOTHERAPY WITH CISPLATIN, VINBLASTINE, AND BLEOMYCIN [J].

JOHNSON, DH ;

HAINSWORTH, JD ;

LINDE, RB ;

GRECO, FA .

MEDICAL AND PEDIATRIC ONCOLOGY, 1984, 12 (04) :233-238

[9] REPRODUCTIVE AND ENDOCRINE GONADAL FUNCTIONS IN ADULTS FOLLOWING MULTIDRUG CHEMOTHERAPY FOR ACUTE LYMPHOBLASTIC OR UNDIFFERENTIATED LEUKEMIA [J].

KREUSER, ED ;

HETZEL, WD ;

HEIT, W ;

HOELZER, D ;

KURRLE, E ;

XIROS, N ;

HEIMPEL, H .

JOURNAL OF CLINICAL ONCOLOGY, 1988, 6 (04) :588-595

[10] CHRONIC GONADAL TOXICITY IN PATIENTS WITH TESTICULAR CANCER AFTER CHEMOTHERAPY [J].

KREUSER, ED ;

HARSCH, U ;

HETZEL, WD ;

SCHREML, W .

EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1986, 22 (03) :289-294

← 1 2 →