THYROID AUTOIMMUNITY

被引：18

作者：

CHAMPION, BR

COOKE, A

RAYNER, DC

机构：

[1] UNIV ALBERTA,DEPT PATHOL,EDMONTON T6G 2R7,ALBERTA,CANADA

[2] UNIV CAMBRIDGE,DEPT PATHOL,DIV IMMUNOL,CAMBRIDGE CB2 1QP,ENGLAND

来源：

CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 06期

关键词：

D O I：

10.1016/0952-7915(92)90060-R

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antigenic structure remains a major focus in thyroid immunology. The genes for three major thyroid antigens-thyroglobulin, thyroid peroxidase and the thyrotropin receptor-were sequenced in the late 1980's, and epitopes for antibody and T cells have been reported within the last year. In addition, new evidence for selective use of T-cell receptor V gene segments in human thyroid infiltrates may point the way to specific immunotherapy.

引用

收藏

页码：770 / 778

页数：9

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