DIHYDROFOLATE-REDUCTASE - X-RAY STRUCTURE OF BINARY COMPLEX WITH METHOTREXATE

被引：320

作者：

MATTHEWS, DA

ALDEN, RA

BOLIN, JT

FREER, ST

HAMLIN, R

XUONG, N

KRAUT, J

POE, M

WILLIAMS, M

HOOGSTEEN, K

机构：

[1] UNIV CALIF SAN DIEGO, DEPT CHEM, LA JOLLA, CA 92093 USA

[2] UNIV CALIF SAN DIEGO, DEPT BIOL, LA JOLLA, CA 92093 USA

[3] UNIV CALIF SAN DIEGO, DEPT PHYS, LA JOLLA, CA 92093 USA

[4] MERCK INST THERAPEUT RES, RAHWAY, NJ 07065 USA

来源：

关键词：

D O I：

10.1126/science.17920

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：452 / 455

页数：4

共 32 条

[1] STRUCTURE-FUNCTION RELATIONSHIPS IN LACTATE-DEHYDROGENASE
ADAMS, MJ
BUEHNER, M
CHANDRASEKHAR, K
FORD, GC
HACKERT, ML
LILJAS, A
ROSSMANN, MG
SMILEY, IE
ALLISON, WS
EVERSE, J
KAPLAN, NO
TAYLOR, SS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (07) : 1968 - 1972
[2] BAKER BR, 1967, DESIGN ACTIVE SITE D, P192
[3] Bennett C. H., COMMUNICATION
[4] SIMILARITY IN SEQUENCE OF ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE WITH OTHER PYRIDINE NUCLEOTIDE REQUIRING ENZYMES
BENNETT, CD
[J]. NATURE, 1974, 248 (5443) : 67 - 68
[5] BERTINO JR, 1972, CANCER CHEMOTHERAPY, V2, P9
[6] BLAKLEY R, COMMUNICATION
[7] BLAKLEY RL, 1969, BIOCH FOLIC ACID REL, P58
[8] 3-DIMENSIONAL STRUCTURE OF D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
BUEHNER, M
FORD, GC
MORAS, D
OLSEN, KW
ROSSMANN, MG
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1974, 90 (01) : 25 - +
[9] MECHANISM OF ACTION OF TRIMETHOPRIM-SULFAMETHOXAZOLE .2.
BURCHALL, JJ
[J]. JOURNAL OF INFECTIOUS DISEASES, 1973, 128 : S437 - S441
[10] STRUCTURE OF YEAST PHOSPHOGLYCERATE MUTASE
CAMPBELL, JW
WATSON, HC
HODGSON, GI
[J]. NATURE, 1974, 250 (5464) : 301 - 303