ANTINEOPLASTIC AGENTS .190. ISOLATION AND STRUCTURE OF THE CYCLODEPSIPEPTIDE DOLASTATIN-14

被引：53

作者：

PETTIT, GR

KAMANO, Y

HERALD, CL

DUFRESNE, C

BATES, RB

SCHMIDT, JM

CERNY, RL

KIZU, H

机构：

[1] ARIZONA STATE UNIV,DEPT CHEM,TEMPE,AZ 85287

[2] UNIV ARIZONA,DEPT CHEM,TUCSON,AZ 85721

[3] UNIV NEBRASKA,DEPT CHEM,MIDWEST CTR MASS SPECT,LINCOLN,NE 68588

[4] HOKURIKU UNIV,SCH PHARM,KANAZAWA,ISHIKAWA 92011,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 10期

关键词：

D O I：

10.1021/jo00297a001

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: The Indian Ocean sea hare Dolabella auricularia has been found to contain a novel cytostatic (PS ED50 0.022 µg/mL) cyclodepsipeptide designated dolastatin 14. Structure 1 was assigned dolastatin 14 and was deduced primarily by a series of 2D NMR studies at high field (400 MHz). © 1990, American Chemical Society. All rights reserved.

引用

页码：2989 / 2990

页数：2

共 12 条

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