GEOGRAPHICAL VARIATION IN ENDOCRINE FUNCTION AND ITS RELATION TO BREAST-CANCER INCIDENCE - SOME GENERAL-CONSIDERATIONS

被引：6

作者：

BULBROOK, RD ^{[1
]}

机构：

[1] UNIV GLASGOW, DEPT BIOCHEM, IMPERIAL CANC RES FUND LAB, GLASGOW G12 8QQ, SCOTLAND

来源：

BREAST CANCER RESEARCH AND TREATMENT | 1991年 / 18卷

关键词：

BREAST CANCER; HORMONES; ESTROGENS; RISK; GEOGRAPHICAL VARIATION;

D O I：

10.1007/BF02633525

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Abnormalities in endocrine function are not a determinant of risk of breast cancer within countries, and racial differences in this function do not explain geographical variation in risk. It is suggested that hormonal status is related to tumor growth rates and hence to age at diagnosis, recurrence rates after primary treatment, and survival. Such evidence as there is points in this direction, but it still remains to be finally established whether the disease runs a similar course in all countries when patients are standardised for factors known to affect prognosis.

引用

页码：S37 / S40

页数：4

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