DYNAMICS OF BONE ALUMINUM OVER ONE-YEAR OF FUNCTIONING RENAL GRAFT

被引：3

作者：

BERTOLONE, G

ANDRIANI, M

BONUCCI, E

BALLANTI, P

COSTANTINI, S

GIORDANO, R

MATTIELLO, G

CALCONI, G

MARESCA, MC

GALARDI, N

CALZAVARA, P

NORDIO, M

PICCOLI, A

机构：

[1] UNIV PADUA,IST MED INTERNA,CATTEDRA NEFROL,VIA GIUSTINIANI 2,I-35128 PADUA,ITALY

[2] UNIV ROMA LA SAPIENZA,DIPARTIMENTO BIOPATOL UMANA,I-00185 ROME,ITALY

[3] IST SUPER SANITA,I-00161 ROME,ITALY

[4] PRESIDIO MULTIZONALE PREVENZ,VENICE,ITALY

[5] DIV NEFROL & DIALISI,DOLO,ITALY

[6] DIV NEFROL & DIALISI,TREVISO,ITALY

来源：

NEPHRON | 1993年 / 64卷 / 04期

关键词：

BONE ALUMINUM; SERUM ALUMINUM; URINE ALUMINUM; BONE HISTOMORPHOMETRY; RENAL TRANSPLANTATION; RENAL OSTEODYSTROPHY;

D O I：

10.1159/000187397

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The concentration of aluminum (Al) in serum, urine, and bone, as well as bone histomorphometry parameters were studied before and 1 year after kidney transplantation (Tx) in 20 dialyzed patients. One year after Tx, serum Al fell significantly from 50.3 +/- 8.8 to 23.9 +/- 2.7 mug/l, (53% fall). Bone Al content also decreased significantly from 62.9 +/- 9.0 to 36.5 +/- 7.0 mug/kg bone weight, but urine Al excretion was still above normal. The repeat bone histomorphometric examination showed a good recovery of bone resorption which correlated well with serum parathyroid hormone levels, but poorer recovery of indices of bone formation and of the extent of Al deposits in the bone as shown by aluminon staining.

引用

页码：540 / 546

页数：7

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