QUINAZOLINES AND 1,4-BENZODIAZEPINES .38. REACTION OF HYDRAZINES WITH 6-CHLORO-2-CHLOROMETHYL-4-PHENYLQUINAZOLINE 3-OXIDE

被引：9

作者：

DERIEG, ME

FRYER, RI

STERNBAC.LH

机构：

[1] Research Division, Hoffmann-La Roche Inc., Nutley 10, NJ

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 09期

关键词：

D O I：

10.1039/j39680001103

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of hydrazines with 6-chloro-2-chloromethyl-4- phenylquinazoline 3-oxide have been investigated. In the case of hydrazine, a benzodiazepine was obtained, and some of its reactions with acetylating agents are discussed. When 1,1-dimethylhydrazine and methylhydrazine were used, quinazoline hydrazones were obtained. A mechanism is suggested.

引用

页码：1103 / &

共 12 条

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