NONSPECIFIC DEFENSE-MECHANISM - THE ROLE OF NITRIC-OXIDE

被引：246

作者：

LIEW, FY ^{[1
]}

COX, FEG ^{[1
]}

机构：

[1] KINGS COLL, DIV BIOMOLEC SCI, LONDON W8 7AH, ENGLAND

来源：

IMMUNOPARASITOLOGY TODAY-A COMBINED ISSUE OF IMMUNOLOGY TODAY AND PARASITOLOGY TODAY | 1991年 / 03期

关键词：

D O I：

10.1016/S0167-5699(05)80006-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There is a marked contrast between the extraordinary complexity and specificity of the adaptive immune response and the limited number of effector mechanisms that it can direct. Recently, a great deal of interest has focused on the possible role of nitric oxide (NO) in one of these mechanisms. Here F.Y. Liew and Frank Cox examine the evidence supporting a role for NO in parasitic disease and suggest possible mechanisms of NO-mediated parasite damage. © 1991 Elsevier Science Publishers Ltd, UK.

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页码：A17 / A21

页数：5

相关论文

共 75 条

[1]

ADAMS LB, 1990, J IMMUNOL, V144, P2725

[2] ENDOTOXIN AND DOUBLE STRANDED RNA RENDER MACROPHAGES CYTOTOXIC [J].

ALEXANDER, P ;

EVANS, R .

NATURE-NEW BIOLOGY, 1971, 232 (29) :76-+

[3] A COMPILATION OF SPECIFIC BIMOLECULAR RATE CONSTANTS FOR REACTIONS OF HYDRATED ELECTRONS HYDROGEN ATOMS AND HYDROXYL RADICALS WITH INORGANIC AND ORGANIC COMPOUNDS IN AQUEOUS SOLUTION [J].

ANBAR, M ;

NETA, P .

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1967, 18 (07) :493-&

[4] APPARENT HYDROXYL RADICAL PRODUCTION BY PEROXYNITRITE - IMPLICATIONS FOR ENDOTHELIAL INJURY FROM NITRIC-OXIDE AND SUPEROXIDE [J].

BECKMAN, JS ;

BECKMAN, TW ;

CHEN, J ;

MARSHALL, PA ;

FREEMAN, BA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (04) :1620-1624

[5] TUMOR NECROSIS FACTOR-ALPHA IN COMBINATION WITH INTERFERON-GAMMA, BUT NOT WITH INTERLEUKIN-4 ACTIVATES MURINE MACROPHAGES FOR ELIMINATION OF LEISHMANIA-MAJOR AMASTIGOTES [J].

BOGDAN, C ;

MOLL, H ;

SOLBACH, W ;

ROLLINGHOFF, M .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1990, 20 (05) :1131-1135

[6]

BURCHETT SK, 1988, J IMMUNOL, V140, P3473

[7] REASSESSMENT OF THE ROLE OF SPLENIC LEUKOCYTE OXIDATIVE ACTIVITY AND MACROPHAGE ACTIVATION IN EXPRESSION OF IMMUNITY TO MALARIA [J].

CAVACINI, LA ;

GUIDOTTI, M ;

PARKE, LA ;

MELANCONKAPLAN, J ;

WEIDANZ, WP .

INFECTION AND IMMUNITY, 1989, 57 (12) :3677-3682

[8]

CHEDID L, 1979, IMMUNOSTIMULATION, V2

[9]

CHEDID L, 1979, IMMUNOSTIMULATION, V1

[10]

CHEN LP, 1987, J IMMUNOL, V139, P4096

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