ISODAURINOL, AN ARYLNAPHTHALENE LIGNAN FROM HAPLOPHYLLUM-CAPPADOCICUM

Six lignans, isodaurinol, daurinol,justicidin A,justicidin B, diphyllin, and (-)-matairesinol,four furoquinoline alkaloids, dictamnine, robustine, haplopine, and skimmianine, and two coumarins, scopoletin and seselin have been isolated from Haplophyllum cappadocicum, a plant native to eastern Turkey. Isodaurinol, the novel arylnaphthalene lignan, is a structural isomer of the already known daurinol. This is also the first report of the isolation of (-)-matairesinol from the genus Haplophyllum. The structures of the compounds described were established by spectroscopic analyses.