CLONING AND NUCLEOTIDE-SEQUENCE OF CDNA-ENCODING ASP-HEMOLYSIN FROM ASPERGILLUS-FUMIGATUS

被引：78

作者：

EBINA, K ^{[1
]}

SAKAGAMI, H ^{[1
]}

YOKOTA, K ^{[1
]}

KONDO, H ^{[1
]}

机构：

[1] TOHOKU UNIV,SCH MED,DEPT ANAT,SENDAI,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1994年 / 1219卷 / 01期

关键词：

ASP-HEMOLYSIN; CDNA; NUCLEOTIDE SEQUENCE; (A-FUMIGATUS);

D O I：

10.1016/0167-4781(94)90258-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nucleotide sequence of a cDNA encoding Asp-hemolysin from Aspergillus fumigatus was clarified. The deduced amino acid sequence was shown to contain a set of negatively charged domains similar to portions of the cysteine-rich sequence in the ligand-binding domain of LDL-receptor. A potential signal sequence was also identified in the N-terminal domain of the deduced amino acid sequence.

引用

收藏

页码：148 / 150

页数：3

相关论文

共 11 条

[1]

CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2

[2] RECEPTOR-MEDIATED ENDOCYTOSIS - CONCEPTS EMERGING FROM THE LDL RECEPTOR SYSTEM [J].

GOLDSTEIN, JL ;

BROWN, MS ;

ANDERSON, RGW ;

RUSSELL, DW ;

SCHNEIDER, WJ .

ANNUAL REVIEW OF CELL BIOLOGY, 1985, 1 :1-39

[3] HUMAN APOLIPOPROTEIN-B - STRUCTURE OF CARBOXYL-TERMINAL DOMAINS, SITES OF GENE-EXPRESSION, AND CHROMOSOMAL LOCALIZATION [J].

KNOTT, TJ ;

RALL, SC ;

INNERARITY, TL ;

JACOBSON, SF ;

URDEA, MS ;

LEVYWILSON, B ;

POWELL, LM ;

PEASE, RJ ;

EDDY, R ;

NAKAI, H ;

BYERS, M ;

PRIESTLEY, LM ;

ROBERTSON, E ;

RALL, LB ;

BETSHOLTZ, C ;

SHOWS, TB ;

MAHLEY, RW ;

SCOTT, J .

SCIENCE, 1985, 230 (4721) :37-43

[4] IMPROVED TOOLS FOR BIOLOGICAL SEQUENCE COMPARISON [J].

PEARSON, WR ;

LIPMAN, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (08) :2444-2448

[5]

Sambrook J., 1989, MOL CLONING LAB MANU

[6] DNA SEQUENCING WITH CHAIN-TERMINATING INHIBITORS [J].

SANGER, F ;

NICKLEN, S ;

COULSON, AR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5463-5467

[7] THE LDL RECEPTOR GENE - A MOSAIC OF EXONS SHARED WITH DIFFERENT PROTEINS [J].

SUDHOF, TC ;

GOLDSTEIN, JL ;

BROWN, MS ;

RUSSELL, DW .

SCIENCE, 1985, 228 (4701) :815-822

[8] CLASSIFICATION OF MICROBIAL, PLANT AND ANIMAL CYTOLYSINS BASED ON THEIR MEMBRANE-DAMAGING EFFECTS ON HUMAN-FIBROBLASTS [J].

THELESTAM, M ;

MOLLBY, R .

BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 557 (01) :156-169

[9] A NEW METHOD FOR PREDICTING SIGNAL SEQUENCE CLEAVAGE SITES [J].

VONHEIJNE, G .

NUCLEIC ACIDS RESEARCH, 1986, 14 (11) :4683-4690

[10] THE HUMAN LDL RECEPTOR - A CYSTEINE-RICH PROTEIN WITH MULTIPLE ALU SEQUENCES IN ITS MESSENGER-RNA [J].

YAMAMOTO, T ;

DAVIS, CG ;

BROWN, MS ;

SCHNEIDER, WJ ;

CASEY, ML ;

GOLDSTEIN, JL ;

RUSSELL, DW .

CELL, 1984, 39 (01) :27-38