CHRONIC ACTIVE EPSTEIN-BARR-VIRUS INFECTION IN AN ADULT

被引：9

作者：

SAKAMOTO, T

UEMURA, M

FUKUI, H

YOSHIKAWA, M

FUKUI, K

KINOSHITA, K

KOJIMA, H

MATSUMORI, T

TSUJII, T

SUMAZAKI, R

机构：

[1] From the Third Department of Internal Medicine, Nara Medical University, Kashihara

[2] Department of Pediatrics, University of Tsukuba Institute of Clinical Medicine, Tsukuba

来源：

INTERNAL MEDICINE | 1992年 / 31卷 / 10期

关键词：

HEPATOSPLENOMEGALY; PANCYTOPENIA; LIVER DISTURBANCE; SOUTHERN BLOT HYBRIDIZATION;

D O I：

10.2169/internalmedicine.31.1190

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a rare adult case of chronic active Epstein-Barr virus (EBV) infection. A 54-year-old woman was admitted to our hospital with intermittent fever, weight loss, hepatosplenomegaly, pancytopenia and liver disturbance. In serological tests for EBV, anti-virus capsid antigen (VCA)-IgG antibody and anti-early antigen (EA)-IgG antibody were markedly elevated and anti-EBV nuclear antigen (EBNA) antibody was negative. EBV genome was detected in the bone marrow nucleated cells and peripheral lymphocytes by Southern blot hybridization. The patient developed left facial edema, bilateral breast tumor and pneumonia. She died one year after admission in spite of the administration of prednisolone, interferon and acyclovir.

引用

页码：1190 / 1196

页数：7

共 23 条

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