PLASMA-PROTEIN BINDING OF NITROXYNIL IN SEVERAL SPECIES

被引：18

作者：

ALVINERIE, M ^{[1
]}

FLOCH, R ^{[1
]}

GALTIER, P ^{[1
]}

机构：

[1] LAB RHONE MERIEUX,F-31057 TOULOUSE,FRANCE

来源：

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS | 1991年 / 14卷 / 02期

关键词：

D O I：

10.1111/j.1365-2885.1991.tb00819.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The binding of nitroxynil to total plasma proteins of cows, sheep and rabbits was characterized using equilibrium dialysis. The data indicate clearly that nitroxynil was highly (97-98%) bound to plasma protein of each animal. This linear binding would be due to the particular power exerted by serum albumin. The results are in good agreement with known pharmacokinetic properties of nitroxynil in domestic species.

引用

页码：170 / 173

页数：4

共 10 条

[1] PREDNISOLONE BINDING TO PLASMA-PROTEINS IN DOMESTIC SPECIES [J].