CONFORMATIONAL DYNAMICS ASSOCIATED WITH PHOTOSWITCHABLE BINDING OF SPIROPYRAN-MODIFIED CONCANAVALIN-A

被引：14

作者：

ZAHAVY, E ^{[1
]}

RUBIN, S ^{[1
]}

WILLNER, I ^{[1
]}

机构：

[1] HEBREW UNIV JERUSALEM,FARKAS CTR LIGHT INDUCED PROC,IL-91904 JERUSALEM,ISRAEL

来源：

MOLECULAR CRYSTALS AND LIQUID CRYSTALS SCIENCE AND TECHNOLOGY SECTION A-MOLECULAR CRYSTALS AND LIQUID CRYSTALS | 1994年 / 246卷

关键词：

D O I：

10.1080/10587259408037813

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Spiropyran modified concanavalin A, Con. A, reveals photoregulated binding towards monosaccharides. The association constants of the substrate towards the spiro-Con A and the kinetics of the association processes are photostimulated. These photostimulated properties are originated from a structural perturbation of the protein upon photoisomerization of spiro-Con. A to the zwitterionic Con. A. Time resolved light scattering reveals that the structural change of the protein involves a shrinkage.

引用

页码：195 / 199

页数：5

共 13 条

[1] LIGHT-INDUCED ENZYME ACTIVITY CHANGES ASSOCIATED WITH PHOTOISOMERIZATION OF BOUND SPIROPYRAN [J].

AIZAWA, M ;

NAMBA, K ;

SUZUKI, S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1977, 182 (01) :305-310

[2] PROTEIN-CARBOHYDRATE INTERACTION .2. INHIBITION STUDIES ON INTERACTION OF CONCANAVALIN A WITH POLYSACCHARIDES [J].

GOLDSTEIN, IJ ;

HOLLERMAN, CE ;

SMITH, EE .

BIOCHEMISTRY, 1965, 4 (05) :876-+

[3]

GUGLIELMETTI R, 1990, PHOTOCHEMISTRY MOL S

[4]

LEHN JM, 1988, ANGEW CHEM INT EDIT, V24, P88

[5] PHOTOPHYSICS, PHOTOCHEMISTRY, KINETICS, AND MECHANISM OF THE PHOTOCHROMISM OF 6'-NITROINDOLINOSPIROPYRAN [J].

LENOBLE, C ;

BECKER, RS .

JOURNAL OF PHYSICAL CHEMISTRY, 1986, 90 (01) :62-65

[6] MAJOR INITIATIVES FOR OPTICAL COMPUTING [J].

NEFF, JA .

OPTICAL ENGINEERING, 1987, 26 (01) :2-9

[7]

TANFORD C, 1967, PHYSICAL CHEM MACROM

[8] NONLINEAR OPTICAL POLYMER SYSTEMS AND DEVICES [J].

ULRICH, DR .

MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 1988, 160 :1-31

[9] PHOTOREGULATION OF PAPAIN ACTIVITY THROUGH ANCHORING PHOTOCHROMIC AZO GROUPS TO THE ENZYME BACKBONE [J].

WILLNER, I ;

RUBIN, S ;

RIKLIN, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (09) :3321-3325

[10] PHOTOREGULATED BINDING OF SPIROPYRAN-MODIFIED CONCANAVALIN-A TO MONOSACCHARIDE-FUNCTIONALIZED SELF-ASSEMBLED MONOLAYERS ON GOLD ELECTRODES [J].

WILLNER, I ;

RUBIN, S ;

COHEN, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (11) :4937-4938

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