STABLE ORAL AVAILABILITY OF SUSTAINED-RELEASE PROPRANOLOL WHEN CO-ADMINISTERED WITH HYDRALAZINE OR FOOD - EVIDENCE IMPLICATING SUBSTRATE DELIVERY RATE AS A DETERMINANT OF PRESYSTEMIC DRUG-INTERACTIONS

被引：26

作者：

BYRNE, AJ

MCNEIL, JJ

HARRISON, PM

LOUIS, W

TONKIN, AM

MCLEAN, AJ

机构：

[1] BAKER MED RES INST,CLIN PHARMACOL LAB,PRAHRAN,VIC 3181,AUSTRALIA

[2] UNIV MELBOURNE,AUSTIN HOSP,DEPT MED,CLIN PHARMACOL UNIT,HEIDELBERG,VIC 3084,AUSTRALIA

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1984年 / 17卷

关键词：

D O I：

10.1111/j.1365-2125.1984.tb02427.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：S45 / S50

页数：6

共 17 条

[1] PHARMACOKINETICS OF PROPRANOLOL [J].

BORGSTROM, L ;

JOHANSSON, CG ;

LARSSON, H ;

LENANDER, R .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1981, 9 (04) :419-429

[2]

DAVIES R, 1978, LANCET, V1, P407

[3]

DRUMMER DH, 1981, J PHARM SCI, V70, P1031

[4] PHARMACOKINETICS OF PROPRANOLOL IN NORMAL HEALTHY VOLUNTEERS [J].

GOMENI, R ;

BIANCHETTI, G ;

SEGA, R ;

MORSELLI, PL .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1977, 5 (03) :183-192

[5] THE EFFECT OF HYDRALAZINE ON THE PHARMACOKINETICS OF THREE DIFFERENT BETA-ADRENOCEPTOR ANTAGONISTS - METOPROLOL, NADOLOL, AND ACEBUTOLOL [J].

JACK, DB ;

KENDALL, MJ ;

DEAN, S ;

LAUGHER, SJ ;

ZAMAN, R ;

TENNESON, ME .

BIOPHARMACEUTICS & DRUG DISPOSITION, 1982, 3 (01) :47-54

[6]

LIEDHOLM H, 1983, DRUG NUTR INTERACT, V1, P293

[7]

MACKICHAN JJ, 1978, RES COMMUN CHEM PATH, V20, P531

[8] INTERACTION BETWEEN ORAL PROPRANOLOL AND HYDRALAZINE [J].

MCLEAN, AJ ;

SKEWS, H ;

BOBIK, A ;

DUDLEY, FJ .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 27 (06) :726-732

[9] REDUCTION OF 1ST-PASS HEPATIC-CLEARANCE OF PROPRANOLOL BY FOOD [J].

MCLEAN, AJ ;

ISBISTER, C ;

BOBIK, A ;

DUDLEY, FJ .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (01) :31-34

[10]

MCLEAN AJ, 1978, CLIN PHARMACOL THER, V24, P5

← 1 2 →