CA2+-STORAGE ORGANELLES

被引：41

作者：

KRAUSE, KH ^{[1
]}

机构：

[1] UNIV GENEVA, HOP CANTONAL, DEPT INTERNAL MED, DIV INFECT DIS, CH-1211 GENEVA 4, SWITZERLAND

来源：

FEBS LETTERS | 1991年 / 285卷 / 02期

关键词：

CA2+ PUMP; CA2+ RELEASE CHANNEL; CA2+ STORAGE PROTEIN; SARCOPLASMIC RETICULUM; CALSIOSOME; ENDOPLASMIC RETICULUM;

D O I：

10.1016/0014-5793(91)80806-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Intracellular Ca2+-storage organelles are found in virtually all eukaryotic cells. They play an important role in the regulation of the cytosolic free Ca2+ concentration and, thereby, in the regulation of cellular activity. Ca2+-storage organelles consist, in the simplest model of a Ca2+ pump, of a Ca2+-storage protein and a Ca2+-release channel. The primary structure of these functionally important proteins of Ca2+-storage organelles is similar in different cell types and conserved through evolution. In contrast, their spatial arrangement and, thus, the architecture of Ca2+-storage organelles may vary dramatically from one cell type to anther.

引用

页码：225 / 229

页数：5

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