EFFICIENT METHOD FOR INTRODUCING VINEOMYCIN-FRIDAMYCIN-TYPE SIDE-CHAIN - TOTAL SYNTHESIS OF FRIDAMYCIN-E

被引：15

作者：

MATSUMOTO, T ^{[1
]}

JONA, H ^{[1
]}

KATSUKI, M ^{[1
]}

SUZUKI, K ^{[1
]}

机构：

[1] KEIO UNIV,DEPT CHEM,KOHOKU KU,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(00)93439-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An effective approach for introducing vineomycin-fridamycin-type side chain was developed. Tin-lithium exchange of arylstannane 5 followed by the reaction with chiral aldehyde 6 gave the desired adduct 7. Total synthesis of (R)-(+)-fridamycin E was accomplished.

引用

页码：5103 / 5106

页数：4

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