PATHOGENIC STUDIES AND ANTIGENIC AND SEQUENCE COMPARISONS OF A-EQUINE-ALASKA-1-91 (H3N8) INFLUENZA-VIRUS

被引:2
作者
ALSTAD, AD
SAHU, SP
PEDERSEN, DD
SAARI, DA
KAWAOKA, Y
WEBSTER, RG
机构
[1] US Department of Agriculture, National Veterinary Services Laboratories, Ames, 50010., IA
关键词
D O I
10.1177/104063879300500103
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
An influenza virus, A/equine/Alaska/1/91 (H3N8), was isolated from horses from Alaska with an acute respiratory infection. Pathogenic and serologic studies revealed that this virus is similar to previously isolated equine H3N8 influenza viruses. Antigenic analyses utilizing hemagglutination inhibition and neuraminidase inhibition assays indicated an antigenic drift from the prototype equine H3N8 influenza virus, A/equine/Miami/1/63. Partial sequence analysis of the A/equine/Alaska influenza virus indicated that each of 8 gene sequences are of equine origin.
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页码:8 / 11
页数:4
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