STUDIES ON GLYCAN PROCESSING INHIBITORS - SYNTHESIS OF N-ACETYLHEXOSAMINE ANALOGS AND CYCLIC CARBAMATE DERIVATIVES OF 1-DEOXYNOJIRIMYCIN

被引：27

作者：

KISO, M

KITAGAWA, M

ISHIDA, H

HASEGAWA, A

机构：

[1] Department of Applied Bioorganic Chemistry, Gifu University

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1991年 / 10卷 / 01期

关键词：

D O I：

10.1080/07328309108543888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1-Deoxynojirimycin (1,5-dideoxy-1,5-imino-D-glucitol) was converted, via epoxide intermediates, into a series of N-acetylhexosamine analogs, i. e., 2-acetamido-1,2,5-trideoxy-1,5-imino-D-glucitol, 2-acetamido-1,2,5-trideoxy-1,5-imino-D-mannitol, 2-acetamido-1,2,5-trideoxy-1,5-imino-D-galactitol, and their isomers. The cyclic 5-N,6-O-carbamoyl derivatives of 1-deoxynojirimycin were also prepared.

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页码：25 / 45

页数：21

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