GENETICS OF MAJOR PSYCHIATRIC-DISORDERS

被引：8

作者：

CIARANELLO, RD

CIARANELLO, AL

机构：

[1] Division of Child Psychiatry, Dept. of Psychiat. and Behav. Sci., Stanford Univ. School of Medicine, Stanford

来源：

ANNUAL REVIEW OF MEDICINE | 1991年 / 42卷

关键词：

AFFECTIVE DISORDERS; BIPOLAR ILLNESS; MAJOR DEPRESSIVE DISORDER; SCHIZOPHRENIA; LINKAGE; RFLP; LOD SCORES;

D O I：

10.1146/annurev.me.42.020191.001055

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We review recent studies on the inheritance of affective disorders and schizophrenia. Both groups of diseases have substantial genetic and nongenetic components, and their inheritance does not fit simple Mendelian models. Linkage studies implicate the Xp28 and 11p15 regions as potential disease loci in affective illness, and the 5q11-q13 region in schizophrenia. These conclusions are highly controversial, however, and must be viewed as extremely tentative.

引用

页码：151 / 158

页数：8

共 38 条

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