CYTOLOGY OF TRANSITIONAL-CELL CARCINOMA OF THE URINARY-BLADDER - DIAGNOSTIC YIELD AND HISTOLOGIC BASIS

被引：12

作者：

DIBONITO, L

MUSSE, MM

DUDINE, S

FALCONIERI, G

机构：

[1] Department of Anatomic Pathology, University of Trieste, Trieste

[2] National University, Mogadiscio

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1992年 / 8卷 / 02期

关键词：

UROTHELIAL TUMORS; EXFOLIATIVE CYTOLOGY; CYTOHISTOLOGICAL CORRELATION;

D O I：

10.1002/dc.2840080207

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The diagnostic yield of cytology in histologically proven transitional-cell carcinoma (TCC) of the urinary bladder has been studied in 100 cases. Cytohistologic correlation rates were 20 percent, 61.7 percent, and 92.8 percent, respectively, for grade 1, 2, and 3 tumors. When further evaluated, G2 cases were segregated into 2 subcategories, G2a and G2b, based on histologic preservation of nuclear polarity, pleomorphism, and other cellular irregularities. Correlation rates were rather low for G2a cases (6/18, 33%) and high for G2b cases, (23/29; 79%). The prevalence of atypical cells was 2 (11.1%) cases in G2a and 16 (55.2%) cases in G2b. The results of this study confirm that cytology has an extremely varying diagnostic yield in urinary bladder TCC. Greater cell exfoliation, increased atypia, and a tendency to infiltration of G2b and G3 cases probably account for the higher diagnostic yield detected in these groups.

引用

页码：124 / 127

页数：4

共 19 条

[1]

Koss LG, Deitch D, Ramanathan R, Sherman AB, Diagnostic value of cytology of voided urine, Acta Cytol, 29, pp. 810-816, (1985)

[2]

Murphy WM, Soloway MS, Jukkola AF, Crabtree WN, Ford KS, Urinary cytology and bladder cancer, Cancer, 53, pp. 1555-1565, (1984)

[3]

Soloway MS, Evaluation and management of patients with superficial bladder cancer, Urol Clin North Am, 14, pp. 771-779, (1987)

[4]

Cant JD, Murphy WM, Soloway MS, Prognostic significance of urine cytology on initial follow‐up after intravescical mitomycin C for superficial bladder cancer, Cancer, 57, pp. 2119-2122, (1986)

[5]

Shenoy UA, Colby TV, Schumann B, Reliability of urinary cytodiagnosis in urothelial neoplasms, Cancer, 56, pp. 2041-2045, (1985)

[6]

Kern WH, The diagnostic accuracy of sputum and urine cytology, Acta Cytol, 32, pp. 651-654, (1988)

[7]

Kern WH, The cytology of transitional cell carcinoma of the urinary bladder, Acta Cytol, 19, pp. 420-428, (1975)

[8]

Muller F, Kraft R, Zingg E, Exfoliative cytology after transurethral resection of superficial bladder tumours, Br J Urol, 57, pp. 530-534, (1985)

[9]

Feeney MJ, Mullenix RB, Prentiss RI, Martin PL, Slate TA, Cytological studies of the urine: preliminary report, J Urol, 79, pp. 589-595, (1958)

[10]

Harrison JH, Botsfood TW, Tucker MR, The use of smear of urinary sediment in the diagnosis and management of neoplasms of the kidney and bladder, Surg Gynecol Obstet, 92, pp. 129-139, (1951)

← 1 2 →