CATION-PI INTERACTION BETWEEN THE TRIMETHYLAMMONIUM MOIETY AND THE AROMATIC RING WITH INDOLE-3-ACETIC-ACID CHOLINE ESTER, A MODEL-COMPOUND FOR MOLECULAR RECOGNITION BETWEEN ACETYLCHOLINE AND ITS ESTERASE - AN X-RAY STUDY

被引：30

作者：

AOKI, K

MURAYAMA, K

NISHIYAMA, H

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 21期

关键词：

D O I：

10.1039/c39950002221

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

X-Ray analysis of indole-3-acetic acid choline ester, a model compound for molecular recognition between the neurotransmitter acetylcholine and its esterase, shows that the quaternary trimethylammonium group is folded back to make a close contact with the indole ring through the cation-pi interaction; H-1 NMR spectroscopy confirms this type of interaction also occurs in solution.

引用

页码：2221 / 2222

页数：2

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