A UNIQUE CHROMOSOME-TRANSLOCATION, T(11-12-18)(Q13-Q13-Q12), IN PRIMARY LUNG LYMPHOMA

被引：12

作者：

KUBONISHI, I

SUGITO, S

KOBAYASHI, M

ASAHI, Y

TSUCHIYA, T

YAMASHIRO, T

MIYOSHI, I

机构：

[1] KOCHI MED SCH,DEPT SURG,KOCHI 783,JAPAN

[2] SHIONOGI BIOMED LABS,OSAKA,JAPAN

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 82卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)00290-R

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

`A 54-year-old mon with a primary lung lymphoma of mucosa-associated lymphoid tissue (MALT) origin whose tumor cells had a t(11;12;18)(q13;q13;q12) chromosome abnormality is described. The morphologic, immunologic, and molecular biologic investigations showed that the patient's lung tumor consisted of small lymphoid cells that expressed monoclonal IgM, kappa-type immunoglobulin, and immunoglobulin gene (J(H) and C-kappa) rearrangements. Cytogenetic study revealed that the tumor cells contained a unique chromosome translocation, t(11;12;18) (q13;q13;q12), that has not been reported previously in lymphoma.

引用

页码：54 / 56

页数：3

共 19 条

[1] CYTOGENETIC AND MOLECULAR STUDIES OF T(14-18) AND T(14-19) IN NODAL AND EXTRANODAL B-CELL LYMPHOMA [J].