STERIC CONFIGURATION AND POLYMORPHIC OXIDATION OF LIPOPHILIC BETA-ADRENOCEPTOR BLOCKING-AGENTS - INVIVO INVITRO CORRELATIONS

被引：25

作者：

DAYER, P ^{[1
]}

LEEMANN, T ^{[1
]}

GUT, J ^{[1
]}

KRONBACH, T ^{[1
]}

KUPFER, A ^{[1
]}

FRANCIS, R ^{[1
]}

MEYER, UA ^{[1
]}

机构：

[1] UNIV BASEL,BIOCTR,DEPT PHARMACOL,CH-4056 BASEL,SWITZERLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1985年 / 34卷 / 03期

关键词：

D O I：

10.1016/0006-2952(85)90058-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：399 / 400

页数：2

共 10 条

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[2] CONTRIBUTION OF THE GENETIC STATUS OF OXIDATIVE-METABOLISM TO VARIABILITY IN THE PLASMA-CONCENTRATIONS OF BETA-ADRENOCEPTOR BLOCKING-AGENTS
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[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 24 (06) : 797 - 799
[3] DEFECTIVE HYDROXYLATION OF BUFURALOL ASSOCIATED WITH SIDE-EFFECTS OF THE DRUG IN POOR METABOLIZERS
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[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 13 (05) : 750 - 752
[4] THE GENETIC-CONTROL OF BUFURALOL METABOLISM IN MAN
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[J]. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 1982, 7 (01) : 73 - 77
[5] KINETICS AND METABOLISM OF (+)-BUFURALOL, (-)-BUFURALOL AND (+/-)-BUFURALOL
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[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 23 (06) : 529 - 533
[6] FRANCIS RJ, 1976, EUR J DRUG METAB PH, V1, P113
[7] GUT J, 1984, FEBS LETT
[8] LEEMANN T, 1984, EXPERIENTIA, V40, P647
[9] DEFECTIVE METABOLISM OF METOPROLOL IN POOR HYDROXYLATORS OF DEBRISOQUINE
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[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 14 (02) : 301 - 303
[10] BUFURALOL METABOLISM IN HUMAN-LIVER - A SENSITIVE PROBE FOR THE DEBRISOQUINE-TYPE POLYMORPHISM OF DRUG OXIDATION
MINDER, EI
MEIER, PJ
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MINDER, C
MEYER, UA
[J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1984, 14 (03) : 184 - 189

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