MICROBIAL TRANSFORMATIONS .18. REGIOSPECIFIC PARA-HYDROXYLATION OF AROMATIC CARBAMATES MEDIATED BY THE FUNGUS BEAUVERIA-SULFURESCENS

被引：31

作者：

VIGNE, B ^{[1
]}

ARCHELAS, A ^{[1
]}

FURSTOSS, R ^{[1
]}

机构：

[1] FAC SCI LUMINY,CHIM ORGAN & BIOORGAN LAB,70 ROUTE LEON LACHAMP,CASE 901,F-13288 MARSEILLE 9,FRANCE

来源：

TETRAHEDRON | 1991年 / 47卷 / 08期

关键词：

D O I：

10.1016/S0040-4020(01)86421-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bioconversion of various N-phenyl carbamates bearing alkyl groups of increasing size have been studied. These biotransformations, achieved by the fungus Beauveria sulfurescens, led to the highly regiospecific para-hydroxylation of most of the substrates. For compounds of higher lipophilic character, a double regio- and stereospecific hydroxylation process occurred, which included aromatic and alkyl hydroxylation.

引用

页码：1447 / 1458

页数：12

共 17 条

[1] MICROBIAL TRANSFORMATIONS .8. 1ST EXAMPLE OF A HIGHLY ENANTIOSELECTIVE MICROBIOLOGICAL HYDROXYLATION PROCESS [J].