COLOR-CODED DUPLEX SONOGRAPHY AND ULTRASOUND CONTRAST AGENT FOR THE EXAMINATION OF PERIPHERAL ARTERIES - 1ST CLINICAL-RESULTS

被引:17
作者
FOBBE, F [1 ]
OHNESORGE, I [1 ]
REICHEL, M [1 ]
DOLLINGER, P [1 ]
SCHURMANN, R [1 ]
WOLF, KJ [1 ]
机构
[1] SCHERING AG,BERLIN,GERMANY
来源
ULTRASCHALL IN DER MEDIZIN | 1992年 / 13卷 / 04期
关键词
COLOR CODED DUPLEX SONOGRAPHY; ULTRASOUND CONTRAST MEDIA; PERIPHERAL ARTERIES;
D O I
10.1055/s-2007-1005308
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Ultrasound contrast agents (US-CA) amplify reflected sound waves. Most substances used as contrast agents are destroyed when passing the lungs. SH U 508 is a new US-CA that can pass the lungs without impairment after peripheral intravenous application. In a clinical trial of this US-CA, we investigated its effect on the visualization of blood movement in peripheral arteries by color-coded Duplex sonography (CCDS). The leg arteries of 20 patients with severe chronic arterial occlusion were examined by CCDS (QAD I and Platinum) after i.v. application of the US-CA. After passage of the pulmonary capillaries, the US-CA amplified blood flow signals in the arterial system in a dose-dependent manner with both systems used. Undesired side-effects were not observed. The amplification produced by appropriate concentrations of the US-CA markedly improved the visualization of blood movement. Further studies are required to determine the optimal dosage and application technique as well as the indication for using this US-CA.
引用
收藏
页码:193 / 198
页数:6
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