EFFECT OF THERAPY WITH OXYGEN UNDER HIGH-PRESSURE ON REGIONAL CEREBRAL BLOOD-FLOW IN THE INTERVAL FORM OF CARBON-MONOXIDE POISONING - OBSERVATION FROM SUBTRACTION OF TC-99M HMPAO SPECT BRAIN IMAGING

被引：20

作者：

MAEDA, Y ^{[1
]}

KAWASAKI, Y ^{[1
]}

JIBIKI, I ^{[1
]}

YAMAGUCHI, N ^{[1
]}

MATSUDA, H ^{[1
]}

HISADA, K ^{[1
]}

机构：

[1] KANAZAWA UNIV,SCH MED,DEPT NUCL MED,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

EUROPEAN NEUROLOGY | 1991年 / 31卷 / 06期

关键词：

CARBON MONOXIDE POISONING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TC-99M HEXAMETHYLPROPYLENEAMINE OXIME; OXYGEN UNDER HIGH PRESSURE; REGIONAL CEREBRAL BLOOD FLOW;

D O I：

10.1159/000116698

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Changes in brain images with single photon emission computed tomography (SPECT) using Tc-99m hexamethylpropyleneamine oxime (HMPAO) before and after therapy with oxygen under high pressure (OHP) were measured in a 66-year-old man with the interval form of carbon monoxide (CO) poisoning by a new technique, i.e., subtraction of brain images. This study was performed 187 days after acute CO poisoning, in a state of chronic akinetic mutism that followed a lucid interval. A diffuse, but frontal-dominant, hypoperfusion pattern involving both the gray and white matter was observed in the pre-OHP SPECT image. After OHP, regional cerebral blood flow increased in both the gray and white matter and markedly increased in the frontal cortical regions. The present finding suggests that OHP is effective against the chronic state of the interval form of CO poisoning.

引用

页码：380 / &

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