IMMUNOREACTION OF KERATIN, ACTIN, S-100 PROTEIN AND RAT-EGF IN DUCTLIGATED RAT SALIVARY-GLANDS

被引：15

作者：

HASHIMOTO, J ^{[1
]}

YAMADA, K ^{[1
]}

OGATA, K ^{[1
]}

TAKAI, Y ^{[1
]}

MORI, M ^{[1
]}

机构：

[1] ASAHI UNIV,SCH DENT,DEPT ORAL & MAXILLOFACIAL SURG,HOZUMI,GIFU 50102,JAPAN

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1992年 / 21卷 / 05期

关键词：

DUCT-LIGATION; KERATIN; RAT-EGF; SALIVARY GLAND; S-100; PROTEIN;

D O I：

10.1111/j.1600-0714.1992.tb00104.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Duct-ligated submandibular and sublingual glands of rats were evaluated immunohistochemically for changes in keratin (MoAb 1164), actin, S-100 protein and rat-EGF (rEGF). Normal salivary glands were reactive for keratin, S-100 protein and rEGF in the granular convoluted tubule (GCT) and duct cells, and for actin in the myoepithelium. Submandibular glands showed a marked reduction of S-100 protein and rEGF staining following duct ligation, and no increased staining of proliferating epithelial cells of the late stage in duct ligated glands. Sublingual glands revealed no marked changes for actin staining in myoepithelial cells, irrespedtive of atrophic changes occurring in acinar and duct cells after duct ligation. Immunohistochemical patterns differed for each type of gland; changes associated with the obstructive lesion were more prominent in the submandibular gland.

引用

页码：214 / 220

页数：7

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