A SIMPLE ROUTE TO METHYL 5S-(BENZOYLOXY)-6-OXOHEXANOATE, A KEY INTERMEDIATE IN LEUKOTRIENE SYNTHESIS

被引：47

作者：

HAYES, R ^{[1
]}

WALLACE, TW ^{[1
]}

机构：

[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)89063-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl 5S-(benzoyloxy)-6-oxohexanoate 2, an intermediate in synthetic routes to the lipoxygenase-derived arachidonic acid metabolite leukotriene B4, is available in three steps from 2-cyclohexen-1-one, using Schreiber's unsymmetrical ozonolysis protocol. © 1990.

引用

页码：3355 / 3356

页数：2

共 24 条

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