BINDING OF THE ILE-VAL AND VAL-VAL EFFECTOR DIPEPTIDES TO THE BINARY ADDUCTS OF BOVINE TRYPSINOGEN WITH KUNITZ AND KAZAL INHIBITORS AS WELL AS THE ACYLATING AGENT PARA-NITROPHENYL PARA-GUANIDINOBENZOATE - A THERMODYNAMIC AND KINETIC-STUDY

被引：8

作者：

ASCENZI, P

AMICONI, G

BOLOGNESI, M

MENEGATTI, E

GUARNERI, M

机构：

[1] UNIV ROME LA SAPIENZA,DIPARTIMENTO SCI BIOCHIM,CNR,CTR BIOL MOLEC,PIAZZALE ALDO MORO 5,I-00185 ROME,ITALY

[2] UNIV PAVIA,DIPARTIMENTO GENET & MICROBIOL,SEZIONE CRISTALLOG,I-27100 PAVIA,ITALY

[3] UNIV FERRARA,DIPARTIMENTO SCI FARMACEUT,I-44100 FERRARA,ITALY

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1987年 / 194卷 / 04期

关键词：

D O I：

10.1016/0022-2836(87)90253-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：751 / 754

页数：4

共 12 条

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[6] TRANSITION OF BOVINE TRYPSINOGEN TO A TRYPSIN-LIKE STATE UPON STRONG LIGAND-BINDING .2. BINDING OF THE PANCREATIC TRYPSIN-INHIBITOR AND OF ISOLEUCINE-VALINE AND OF SEQUENTIALLY RELATED PEPTIDES TO TRYPSINOGEN AND TO P-GUANIDINOBENZOATE-TRYPSINOGEN [J].

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[7] 3-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN PANCREATIC SECRETORY TRYPSIN-INHIBITOR (KAZAL TYPE) AND TRYPSINOGEN AT 1-8 A RESOLUTION - STRUCTURE SOLUTION, CRYSTALLOGRAPHIC REFINEMENT AND PRELIMINARY STRUCTURAL INTERPRETATION [J].

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[10] FUNCTIONAL-SIGNIFICANCE OF FLEXIBILITY IN PROTEINS [J].

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