CLONING OF THE GENE ENCODING STREPTOCOCCIN A-FF22, A NOVEL LANTIBIOTIC PRODUCED BY STREPTOCOCCUS-PYOGENES, AND DETERMINATION OF ITS NUCLEOTIDE-SEQUENCE

被引:62
作者
HYNES, WL [1 ]
FERRETTI, JJ [1 ]
TAGG, JR [1 ]
机构
[1] UNIV OTAGO,DEPT MICROBIOL,DUNEDIN,NEW ZEALAND
关键词
D O I
10.1128/AEM.59.6.1969-1971.1993
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Streptococcin A-FF22 (SA-FF22) is a lantibiotic produced by Streptococcus pyogenes FF22. The nucleotide sequence of the SA-FF22 structural gene (scnA) was determined and shown to encode a 51-amino-acid prepeptide. The proteolytic processing site of the SA-FF22 prepeptide differs from that which characterizes other type A lantibiotics.
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页码:1969 / 1971
页数:3
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