CRAM'S RULE FOR RADICAL REACTIONS

被引:48
作者
GIESE, B [1 ]
DAMM, W [1 ]
DICKHAUT, J [1 ]
WETTERICH, F [1 ]
SUN, SN [1 ]
CURRAN, DP [1 ]
机构
[1] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0040-4039(91)80762-U
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Addition of tris(trimethylsilyl)silyl radicals to chiral ketones 1 yields tert. carbon centered radicals 4 that give predominantly Cram products in hydrogen atom abstraction reactions. Analogous sec. acyloxyalkyl radicals undergo radical C,D- and C,C-bond forming reactions that also follow Cram's rule.
引用
收藏
页码:6097 / 6100
页数:4
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