DICHLOROBORANE-DIMETHYL SULFIDE, A HIGHLY SELECTIVE REDUCING AGENT FOR REDUCTION OF ORGANYL AZIDES TO AMINES

被引：23

作者：

SALUNKHE, AM ^{[1
]}

BROWN, HC ^{[1
]}

机构：

[1] PURDUE UNIV,HC BROWN & RB WETHERILL LABS CHEM,W LAFAYETTE,IN 47907

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 44期

关键词：

D O I：

10.1016/0040-4039(95)01721-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dichloroborane-dimethyl sulfide reduces a variety of organyl azides, such as primary, secondary, tertiary, and aromatic to the corresponding amines in excellent yields. Cycloalkyl and benzylic azides are also readily reduced by this reagent. The reduction of azide with BHCl2.SMe(2) is highly selective and many functional groups, such as halogen, ester, nitrile, aliphatic and aromatic nitro, survive in this process.

引用

页码：7987 / 7990

页数：4

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