SIGNET-RING CELL-CARCINOMA IN HYPERPLASTIC POLYP

被引:18
作者
ZEAIRIARTE, WL
ITSUNO, M
MAKIYAMA, K
HARA, K
HARAGUCHI, M
AJIOKA, Y
机构
[1] SASEBO MUNICIPAL GEN HOSP,DEPT INTERNAL MED,NAGASAKI,JAPAN
[2] NIIGATA UNIV,SCH MED,DEPT PATHOL 1,NIIGATA,JAPAN
关键词
FOVEOLAR MUCIN; GASTRIC HYPERPLASTIC POLYPS; SIGNET RING CELL CARCINOMA;
D O I
10.3109/00365529509089797
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: A polypectomy was performed on a 68-year-old woman who had three gastric hyperplastic polyps. A focal signet ring cell carcinoma was discovered in one of the polyps, which was 2.2 cm in diameter and was located in the antrum. Methods: To study the carcinoma's phenotypic expression, special mucin histochemical stainings were performed. Results: The carcinoma Infiltrated only into the mucosa. Intestinal metaplasia was scant. In the neoplasm neutral and foveolar mucin was predominant over acid mucin. The surrounding hyperplastic foveolar epithelium showed positivity for neutral mucin, and the intestinal metaplasia foci for acid mucin. Conclusions: This neoplasm has a mixed composition of mucins and shares histochemical characteristics with the surrounding hyperplastic foveolar epithelium.
引用
收藏
页码:604 / 608
页数:5
相关论文
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