SYNTHESIS AND CRYSTAL-STRUCTURE OF AN ANALOG OF 2-(ALPHA-LACTYL)THIAMIN, RACEMIC METHYL 2-HYDROXY-2-(2-THIAMIN)ETHYLPHOSPHONATE CHLORIDE TRIHYDRATE - A CONFORMATION FOR A LEAST-MOTION, MAXIMUM-OVERLAP MECHANISM FOR THIAMIN CATALYSIS

被引：33

作者：

TURANO, A

FUREY, W

PLETCHER, J

SAX, M

PIKE, D

KLUGER, R

机构：

[1] UNIV PITTSBURGH,DEPT CRYSTALLOG,PITTSBURGH,PA 15260

[2] VET ADM MED CTR,BIOCRYSTALLOG LAB,PITTSBURGH,PA 15240

[3] UNIV TORONTO,DEPT CHEM,TORONTO M5S 1A1,ONTARIO,CANADA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1982年 / 104卷 / 11期

关键词：

D O I：

10.1021/ja00375a024

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：3089 / 3095

页数：7

共 23 条

[1]

AHMED FR, 1970, CRYSTALLOGRAPHIC COM, P271

[2] STRUCTURAL AND MECHANISTIC STUDIES OF THE ALPHA-KETOGLUTARATE DEHYDROGENASE MULTI-ENZYME COMPLEX FROM ESCHERICHIA-COLI [J].

ANGELIDES, KJ ;

HAMMES, GG .

BIOCHEMISTRY, 1979, 18 (25) :5531-5537

[3] ON THE MECHANISM OF THIAMINE ACTION .4. EVIDENCE FROM STUDIES ON MODEL SYSTEMS [J].

BRESLOW, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (14) :3719-3726

[4]

DUNATHAN HC, 1971, ADV ENZYMOL RAMB, V35, P79

[5]

GALLO AA, 1978, BIOORG CHEM, V4, P147

[6] APPLICATION OF PHASE RELATIONSHIPS TO COMPLEX STRUCTURES .3. OPTIMUM USE OF PHASE RELATIONSHIPS [J].

GERMAIN, G ;

MAIN, P ;

WOOLFSON, MM .

ACTA CRYSTALLOGRAPHICA SECTION A-CRYSTAL PHYSICS DIFFRACTION THEORETICAL AND GENERAL CRYSTALLOGRAPHY, 1971, A 27 (JUL1) :368-&

[7]

Hine J, 1978, ADV PHYS ORG CHEM, V15, P1

[8] PROTON MAGNETIC RESONANCE STUDIES OF PURINE AND PYRIMIDINE DERIVATIES .9. PROTONATION OF PYRIMIDINES IN ACID SOLUTION [J].

JARDETZKY, O ;

PAPPAS, P ;

WADE, NG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (11) :1657-&

[9] THEORETICAL CALCULATIONS ON THIAMINE AND RELATED COMPOUNDS .2. CONFORMATIONAL-ANALYSIS AND ELECTRONIC PROPERTIES OF 2-(ALPHA-HYDROXYETHYL)THIAMINE [J].

JORDAN, F .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (03) :808-813

[10] INTERACTION OF PYRUVATE-THIAMIN DIPHOSPHATE ADDUCTS WITH PYRUVATE DECARBOXYLASE - CATALYSIS THROUGH CLOSED TRANSITION-STATES [J].

KLUGER, R ;

SMYTH, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (05) :1214-1216

← 1 2 3 →