CLONING AND SEQUENCING OF RNA OF HEPATITIS-DELTA-VIRUS ISOLATED FROM HUMAN SERUM

被引：52

作者：

SALDANHA, JA

THOMAS, HC

MONJARDINO, JP

机构：

[1] St. Mary's Hospital, Medical School

来源：

JOURNAL OF GENERAL VIROLOGY | 1990年 / 71卷

关键词：

D O I：

10.1099/0022-1317-71-7-1603

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The RNA of hepatitis delta virus (HDV) 1682 nucleotides long, has been cloned from a human serum isolate. Comparison with the three complete published sequences shows that a region of the HDV genome, between positions 620 and 1350, which contains sequences involved in replication and possibly pathogenicity, is highly conserved.

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页码：1603 / 1606

页数：4

相关论文

共 19 条

[1] AN ULTRAVIOLET-SENSITIVE RNA STRUCTURAL ELEMENT IN A VIROID-LIKE DOMAIN OF THE HEPATITIS DELTA VIRUS [J].

BRANCH, AD ;

BENENFELD, BJ ;

BAROUDY, BM ;

WELLS, FV ;

GERIN, JL ;

ROBERTSON, HD .

SCIENCE, 1989, 243 (4891) :649-652

[2] CLONED FRAGMENT OF THE HEPATITIS DELTA-VIRUS RNA GENOME - SEQUENCE AND DIAGNOSTIC APPLICATION [J].

DENNISTON, KJ ;

HOYER, BH ;

SMEDILE, A ;

WELLS, FV ;

NELSON, J ;

GERIN, JL .

SCIENCE, 1986, 232 (4752) :873-875

[3] VIROID PROCESSING - A MODEL INVOLVING THE CENTRAL CONSERVED REGION AND HAIRPIN-I [J].

DIENER, TO .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (01) :58-62

[4] SELF-CLEAVAGE OF PLUS AND MINUS RNAS OF A VIRUSOID AND A STRUCTURAL MODEL FOR THE ACTIVE-SITES [J].

FORSTER, AC ;

SYMONS, RH .

CELL, 1987, 49 (02) :211-220

[5] A SIMPLE AND VERY EFFICIENT METHOD FOR GENERATING CDNA LIBRARIES [J].

GUBLER, U ;

HOFFMAN, BJ .

GENE, 1983, 25 (2-3) :263-269

[6] THE HEPATITIS DELTA (DELTA) VIRUS POSSESSES A CIRCULAR RNA [J].

KOS, A ;

DIJKEMA, R ;

ARNBERG, AC ;

VANDERMEIDE, PH ;

SCHELLEKENS, H .

NATURE, 1986, 323 (6088) :558-560

[7] MOLECULAR-CLONING OF HEPATITIS DELTA VIRUS-RNA FROM AN INFECTED WOODCHUCK LIVER - SEQUENCE, STRUCTURE, AND APPLICATIONS [J].

KUO, MYP ;

GOLDBERG, J ;

COATES, L ;

MASON, W ;

GERIN, J ;

TAYLOR, J .

JOURNAL OF VIROLOGY, 1988, 62 (06) :1855-1861

[8]

LAI MMC, 1989, 3RD INT S HEP DELT V

[9] MOLECULAR-CLONING AND SEQUENCING OF A HUMAN HEPATITIS-DELTA (DELTA) VIRUS-RNA [J].

MAKINO, S ;

CHANG, MF ;

SHIEH, CK ;

KAMAHORA, T ;

VANNIER, DM ;

GOVINDARAJAN, S ;

LAI, MMC .

NATURE, 1987, 329 (6137) :343-346

[10] BASIS OF HEPATITIS-DELTA VIRUS-DISEASE [J].

NEGRO, F ;

GERIN, JL ;

PURCELL, RH ;

MILLER, RH .

NATURE, 1989, 341 (6238) :111-111