CATALYSIS BY HUMAN-LEUKOCYTE ELASTASE - MECHANISTIC INSIGHTS INTO SPECIFICITY REQUIREMENTS

被引：96

作者：

STEIN, RL

STRIMPLER, AM

HORI, H

POWERS, JC

机构：

[1] STUART PHARMACEUT,DEPT PHARMACOL,PULM PHARMACOL SECT,WILMINGTON,DE 19897

[2] GEORGIA INST TECHNOL,SCH CHEM,ATLANTA,GA 30332

来源：

BIOCHEMISTRY | 1987年 / 26卷 / 05期

关键词：

D O I：

10.1021/bi00379a015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1301 / 1305

页数：5

共 16 条

[1] FARMER DA, 1975, J BIOL CHEM, V250, P7366
[2] CATALYSIS, BINDING AND ENZYME-SUBSTRATE COMPLEMENTARITY
FERSHT, AR
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1974, 187 (1089): : 397 - 407
[3] ACTIVE-SITE MAPPING OF THE SERINE PROTEASES HUMAN-LEUKOCYTE ELASTASE, CATHEPSIN G, PORCINE PANCREATIC ELASTASE, RAT MAST-CELL PROTEASE-I AND PROTEASE-II, BOVINE CHYMOTRYPSIN-A-ALPHA, AND STAPHYLOCOCCUS-AUREUS PROTEASE V-8 USING TRIPEPTIDE THIOBENZYL ESTER SUBSTRATES
HARPER, JW
COOK, RR
ROBERTS, CJ
MCLAUGHLIN, BJ
POWERS, JC
[J]. BIOCHEMISTRY, 1984, 23 (13) : 2995 - 3002
[4] JENCKS WP, 1975, ADV ENZYMOL RAMB, V43, P219
[5] LESTIENNE P, 1980, J BIOL CHEM, V255, P9289
[6] STUDIES ON REACTIVITY OF HUMAN-LEUKOCYTE ELASTASE, CATHEPSIN-G, AND PORCINE PANCREATIC ELASTASE TOWARD PEPTIDES INCLUDING SEQUENCES RELATED TO THE REACTIVE SITE OF ALPHA-1-PROTEASE INHIBITOR (ALPHA-1-ANTITRYPSIN)
MCRAE, B
NAKAJIMA, K
TRAVIS, J
POWERS, JC
[J]. BIOCHEMISTRY, 1980, 19 (17) : 3973 - 3978
[7] METHOD FOR DESIGNING PEPTIDE-SUBSTRATES FOR PROTEASES - TRIPEPTIDYL-P-NITROANILIDE SUBSTRATES FOR SUBTILISIN CARLSBERG
POZSGAY, M
GASPAR, R
BAJUSZ, S
ELODI, P
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1979, 95 (01): : 115 - 119
[8] CATALYSIS BY HUMAN-LEUKOCYTE ELASTASE .5. STRUCTURAL FEATURES OF THE VIRTUAL TRANSITION-STATE FOR ACYLATION
STEIN, RL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (25) : 7768 - 7769
[9] CATALYSIS BY HUMAN-LEUKOCYTE ELASTASE .2. RATE-LIMITING DEACYLATION FOR SPECIFIC PARA-NITROANILIDES AND AMIDES
STEIN, RL
VISCARELLO, BR
WILDONGER, RA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (03) : 796 - 798
[10] CATALYSIS BY HUMAN-LEUKOCYTE ELASTASE - SUBSTRATE STRUCTURAL DEPENDENCE OF RATE-LIMITING PROTOLYTIC CATALYSIS AND OPERATION OF THE CHARGE RELAY SYSTEM
STEIN, RL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (15) : 5111 - 5116

← 1 2 →