INVIVO EFFECTS OF SOLAR-SIMULATED ULTRAVIOLET-IRRADIATION ON ANTIOXIDANT ENZYMES AND LIPID-PEROXIDATION IN HUMAN EPIDERMIS

被引：64

作者：

PUNNONEN, K

AUTIO, P

KIISTALA, U

AHOTUPA, M

机构：

[1] UNIV TURKU,DEPT PHYSIOL,SF-20500 TURKU 50,FINLAND

[2] CENT MIL HOSP,DEPT DERMATOL,HELSINKI,FINLAND

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1991年 / 125卷 / 01期

关键词：

D O I：

10.1111/j.1365-2133.1991.tb06032.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The effects of solar-simulated UV-irradiation on the activity of antioxidant enzymes and the amount of diene conjugation were studied in human epidermis in vivo. A single dose of UV-irradiation was found to result in a transient reduction in superoxide dismutase activity and this was followed by increased amounts of conjugated diene double bonds, an index for oxidative stress. This suggests that in-vivo exposure of human epidermis to solar-simulated UV-irradiation causes changes in the enzymic antioxidant defence system which, in turn. are accompanied by increased level of oxidative stress.

引用

页码：18 / 20

页数：3

共 18 条

[1] PARTIAL MONOSOMY-21, DIMINISHED ACTIVITY OF SUPEROXIDE-DISMUTASE, AND PULMONARY OXYGEN-TOXICITY [J].