CHIRAL SYNTHESIS OF POLYKETIDE-DERIVED NATURAL-PRODUCTS .39. TOTAL SYNTHESIS OF THE POLYETHER ANTIBIOTIC LYSOCELLIN .1. STEREOCONTROLLED SYNTHESIS OF THE C1-C9 AND C16-C23 FRAGMENTS

被引：8

作者：

HORITA, K

INOUE, T

TANAKA, K

YONEMITSU, O

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 38期

关键词：

POLYETHER ANTIBIOTIC; STEREOCONTROLLED SYNTHESIS; HYDROBORATION; WITTIG-HORNER REACTION; MICHAEL REACTION;

D O I：

10.1016/S0040-4039(00)61139-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereocontrolled synthesis of two fragments corresponding to the C1-C-9 (3) and C-16-C23 parts (6) of lysocellin (1) using hydroboration, Wittig-Horner reaction, and Michael reaction in the key steps is described.

引用

页码：5537 / 5540

页数：4

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