ELECTROPHILIC FLUORINATION OF A HIGHLY FUNCTIONALIZED PYRROLE

被引：32

作者：

BARNES, KD

HU, YL

HUNT, DA

机构：

[1] American Cyanamid Co., Agricultural Research Division, Princeton, New Jersey 08543-0400

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 12期

关键词：

D O I：

10.1080/00397919408010180

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bromine-lithium exchange of 3-bromo-1-(triisopropylsilyl) pyrrole 6 followed by treatment with N-fluorobenzenesulfonimide gave the fluoropyrrole 8. Application of this methodology to the highly functionalized pyrrole 1 afforded the fluoropyrrole 4, which was found to be inaccessible by other approaches.

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页码：1749 / 1755

页数：7

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