AGING AND MONOAMINE TURNOVER IN THE LATERAL GENICULATE-NUCLEUS AND VISUAL-CORTEX OF THE RAT

被引：11

作者：

HERRERA, AJ ^{[1
]}

MACHADO, A ^{[1
]}

CANO, J ^{[1
]}

机构：

[1] UNIV SEVILLA,FAC FARM,DEPT BIOQUIM BROMATOL & TOXICOL,C PROF GARCIA GONZALEZ S-N,E-41012 SEVILLE,SPAIN

来源：

NEUROCHEMISTRY INTERNATIONAL | 1993年 / 22卷 / 06期

关键词：

D O I：

10.1016/0197-0186(93)90027-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effects of ageing on the turnover of dopamine, noradrenaline and serotonin in the lateral geniculate nucleus and the visual cortex were evaluated, using high performance liquid chromatography (HPLC) with electrochemical detection. Compared to adult animals, aged rats showed more changes in the visual cortex than in the lateral geniculate nucleus, with dopamine turnover decreased in both structures and noradrenaline turnover unaltered. Changes in serotonin turnover were witnessed only in the visual cortex. A decrease in the monoamine oxidase-A to -B ratio was also observed with increased age for both the lateral geniculate nucleus and visual cortex.

引用

页码：531 / 539

页数：9

共 41 条

[1] MORPHOLOGICAL-CHANGES IN THE RETINA OF AGING RATS
CANO, J
MACHADO, A
REINOSOSUAREZ, F
[J]. ARCHIVES OF GERONTOLOGY AND GERIATRICS, 1986, 5 (01) : 41 - 50
[2] POSTNATAL-DEVELOPMENT IN THE SEROTONIN CONTENT OF BRAIN VISUAL STRUCTURES
CANO, J
REINOSOSUAREZ, F
[J]. DEVELOPMENTAL BRAIN RESEARCH, 1982, 5 (02): : 199 - 201
[3] SIMULTANEOUS MEASUREMENT OF TYROSINE AND TRYPTOPHAN HYDROXYLASE-ACTIVITIES IN BRAIN IN-VIVO USING AN INHIBITOR OF AROMATIC AMINO-ACID DECARBOXYLASE
CARLSSON, A
ATACK, CV
LINDQVIST, M
KEHR, W
DAVIS, JN
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1972, 275 (02) : 153 - +
[4] TURNOVER OF FREE AND CONJUGATED (SULFONYLOXY) DIHYDROXYPHENYLACETIC ACID AND HOMOVANILLIC-ACID IN RAT STRIATUM
DEDEK, J
BAUMES, R
TIENDUC, N
GOMENI, R
KORF, J
[J]. JOURNAL OF NEUROCHEMISTRY, 1979, 33 (03) : 687 - 695
[5] THE SEROTONINERGIC FIBERS IN THE DORSAL LATERAL GENICULATE-NUCLEUS OF THE CAT - DISTRIBUTION AND SYNAPTIC CONNECTIONS DEMONSTRATED WITH IMMUNOCYTOCHEMISTRY
DELIMA, AD
SINGER, W
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1987, 258 (03) : 339 - 351
[6] DEWAR KM, 1989, J PHARMACOL EXP THER, V250, P696
[7] DiBussolo JM, 1983, CHROMATOGR NEWSL, V11, P27
[8] DISTRIBUTION OF DOPAMINE D1 RECEPTORS IN RAT CORTICAL AREAS, NEOSTRIATUM, OLFACTORY-BULB AND HIPPOCAMPUS IN RELATION TO ENDOGENOUS DOPAMINE CONTENTS
DIOP, L
GOTTBERG, E
BRIERE, R
GRONDIN, L
READER, TA
[J]. SYNAPSE, 1988, 2 (04) : 395 - 405
[9] MICROCIRCUITRY OF THE VISUAL-CORTEX
GILBERT, CD
[J]. ANNUAL REVIEW OF NEUROSCIENCE, 1983, 6 : 217 - 247
[10] ACUTE EFFECTS OF LITHIUM ON DOPAMINERGIC RESPONSES - IONTOPHORETIC STUDIES IN THE RAT VISUAL-CORTEX
GOTTBERG, E
MONTREUIL, B
READER, TA
[J]. SYNAPSE, 1988, 2 (04) : 442 - 449

← 1 2 3 4 5 →