DETERMINATION OF SYNEPHRINE IN ORIENTAL PHARMACEUTICAL DECOCTIONS CONTAINING AURANTII NOBILIS PERICARPIUM BY ION-PAIR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：4

作者：

HASHIMOTO, K ^{[1
]}

YASUDA, T ^{[1
]}

OHSAWA, K ^{[1
]}

机构：

[1] TOHOKU COLL PHARMACEUT SCI, 4-1 KOMATSUSHIMA 4 CHOME, AOBA KU, SENDAI, MIYAGI 981, JAPAN

来源：

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 1992年 / 112卷 / 05期

关键词：

SYNEPHRINE; AURANTII-NOBILIS-PERICARPIUM; ION-PAIR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; ORIENTAL PHARMACEUTICAL DECOCTION; QUANTITATIVE DETERMINATION;

D O I：

10.1248/yakushi1947.112.5_327

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A simple method using ion-pair high-performance liquid chromatography was established for the rapid and precise determination of synephrine in oriental pharmaceutical decoctions containing Aurantii Nobilis Pericarpium. An ODS column and a mixture of water, acetonitrile, sodium dodecyl sulfate and phosphoric acid (65 : 35 : 0.5 : 0.1) as a mobile phase were used for the separation. Synephrine was eluted without interference by other co-existing components within 15 min.

引用

页码：327 / 331

页数：5

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