FUNCTIONALIZATION OF UNSATURATED AMIDES - SYNTHESIS OF CHIRAL ALPHA-HYDROXY OR BETA-HYDROXY ACIDS

被引：15

作者：

CARDILLO, G

HASHEM, MA

TOMASINI, C

机构：

[1] Centro per lo Studio della Fisica delle Macromolecole, Dipartimento di Chimica 'G. Ciamician', Università di Bologna, 40126, Bologna, Via Selmi

[2] Department of Chemistry, Jahangirnagar University, Savar, Dhaka

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 05期

关键词：

D O I：

10.1039/p19900001487

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mercury cyclisation of hemiamidals containing a stereogenic centre affords diastereoisomeric mixtures of tetrahydro-1,3-oxazin-4-ones or oxazolidin-4-ones, which are easily separated by silica gel chromatography and hydrolysed to give chiral α- and β-hydroxy acids.

引用

页码：1487 / 1488

页数：2

共 8 条

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