TOXICITY AND CHEMICAL PHENOLOGY OF NORDITERPENOID ALKALOIDS IN THE TALL LARKSPURS (DELPHINIUM SPECIES)

被引：71

作者：

MANNERS, GD ^{[1
]}

PANTER, KE ^{[1
]}

RALPHS, MH ^{[1
]}

PFISTER, JA ^{[1
]}

OLSEN, JD ^{[1
]}

JAMES, LF ^{[1
]}

机构：

[1] USDA ARS,POISONOUS PLANT RES LAB,LOGAN,UT 84321

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1993年 / 41卷 / 01期

关键词：

D O I：

10.1021/jf00025a020

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Eleven norditerpenoid alkaloids found in three tall larkspur species (Delphinium barbeyi, Delphinium occidentale, Delphinium glaucescens) were evaluated as mammalian toxins in a mouse bioassay. Two methylsuccinimido anthranoyllycoctonine (MSAL) norditerpenoid alkaloids (methyllycaconitine and 14-deacetylnudicauline) were determined to have equivalent high toxicity. A third MSAL norditerpenoid, barbinine, was 5 times less toxic. Other norditerpenoid alkaloids tested were found to be significantly less toxic than the MSAL alkaloids. The chemical phenology of the alkaloids in the three larkspurs and the effect of collection site on alkaloid occurrence in D. barbeyi were determined.

引用

页码：96 / 100

页数：5

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