IMPROVED ENZYMATIC-HYDROLYSIS OF HAIR

被引:23
作者
OFFIDANI, C
ROSSI, SS
CHIAROTTI, M
机构
[1] Department of Legal Medicine, Catholic University of the Sacred Heart, 00168 Rome, L. go F. Vito n. l
关键词
HAIR ANALYSIS; DRUG ABUSE; ENZYMATIC DIGESTION;
D O I
10.1016/0379-0738(93)90271-B
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
An enzymatic hair extraction method is proposed for drug analysis. Pronase digestion of various aliquots of hair from a cocaine abuser was preceded by a 2-h incubation with a dithiothreitol solution. The extraction solution was tested to identify possible interferences in the radioimmunoassay and was compared with other hydrolysis methods to assess the results of extraction.
引用
收藏
页码:171 / 174
页数:4
相关论文
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BAUMGARTNER AM, 1979, J NUCL MED, V20, P748
[2]  
MOLLER MR, 1991, 3RD WINT M GERM SOC
[3]   DRUGS IN HAIR - A NEW EXTRACTION PROCEDURE [J].
OFFIDANI, C ;
CARNEVALE, A ;
CHIAROTTI, M .
FORENSIC SCIENCE INTERNATIONAL, 1989, 41 (1-2) :35-39
[4]  
VALENTE D, 1981, CLIN CHEM, V27, P1952